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Trigeminal Neuraligia

Trigeminal Neuraligia

Trigeminal neuralgia is a painful disorder that feels like an electric shock on one side of the face. The trigeminal nerve, which transmits feeling from your face to your brain, is impacted by this chronic pain disorder. Even modest facial stimulation, like brushing your teeth or applying cosmetics, can cause a sharp, severe pain spike if you have trigeminal neuralgia.

At first, you can have brief, moderate attacks. However, if trigeminal neuralgia worsens, it may result in longer, more frequent episodes of excruciating pain. Women are affected with trigeminal neuralgia more frequently than males, and those over 50 are more prone to have it.

Trigeminal neuralgia does not always indicate that a person will always be in pain because there are numerous treatment options accessible. Trigeminal neuralgia is typically adequately treated by doctors using drugs, injections, or surgery.

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Causes

The trigeminal nerve is not functioning normally in trigeminal neuralgia, commonly known as “tic douloureux.” Usually, the issue arises from contact between the trigeminal nerve at the base of your brain and a regular blood vessel, in this case, an artery or vein. The nerve is compressed by this contact, which results in nerve dysfunction.

There are numerous other possible causes of trigeminal neuralgia in addition to the more frequent one of compression by a blood vessel. Sometimes this is associated with multiple sclerosis which involves an autoimmune attack against the myelin sheath that covers some nerves. A tumor compressing the trigeminal nerve can potentially result in trigeminal neuralgia.

Trigeminal neuralgia can occur in certain individuals as a result of brain lesions or other anomalies. Trigeminal neuralgia may also result from stroke, face trauma, or surgical damage in other situations.

Symptoms

Symptoms of trigeminal neuralgia can include one or more of the following patterns:

  • Periods of intense, stabbing, or shooting pain that could be compared to an electric shock
  • Episodes of discomfort that happen on their own or that are brought on by actions like stroking the face, chewing, speaking, or brushing teeth
  • Pain episodes that range in duration from a few seconds to many minutes
  • Pain that results from spasms in the face
  • Attacks that endure for days, weeks, months, or longer in succession; some people go for extended periods of time without experiencing any discomfort.
  • Trigeminal nerve-supplied regions of pain, such as the cheek, jaw, teeth, gums, lips, the eye and forehead.
  • One side of the face experiencing pain at a time.
  • Pain that is localized or distributed throughout a larger area.
  • Pain that sometimes appears as you sleep.
  • Attacks that increase in frequency and severity with time.

TREATMENTS

Your doctor will typically prescribe medication to reduce or block the pain signals that are sent to your brain in order to treat trigeminal neuralgia.

  • Antiseizure medication. Trigeminal neuralgia is typically treated with carbamazepine (Tegretol, Carbatrol, and other brands), which has been demonstrated to be successful in treating this condition. Trigeminal neuralgia may also be treated with valproate, oxcarbazepine (Trileptal, Oxtellar XR), lamotrigine (Lamictal), phenytoin (Dilantin, Phenytek, Cerebyx), and other anticonvulsant medications. Other medications may also be utilized, such as gabapentin (Neurontin, Gralise, Horizant), pregabalin (Lyrica), topiramate (Qsymia, Topamax, and others), and clonazepam (Klonopin).

 

  • Your doctor might change the kind of anticonvulsant you’re taking or up the dosage if the one you’re taking starts to become less effective. Anticonvulsant side effects can include nausea, sleepiness, dizziness, and confusion. Furthermore, genetic testing could be advised before to starting carbamazepine because it can cause a dangerous medication reaction in certain individuals, primarily those of Asian descent.

 

  • Baclofen (Gablofen, Lioresal, Ozobax) and other muscle relaxants can be administered with or without carbamazepine. Drowsiness, nausea, and disorientation are possible side effects.
  • Botox injections. Injections of onabotulinumtoxinA (Botox) may lessen trigeminal neuralgia pain in those whose drugs are no longer effective, according to small trials. Before this treatment is utilized extensively for this ailment, more research must be conducted.
  • Decompression of microvascular structures. To prevent the nerve from malfunctioning, this technique entails shifting or eliminating blood vessels that come into touch with the trigeminal nerve. In microvascular decompression, the side of your pain is incised behind the ear by your doctor. Your surgeon will next create a soft cushion between the trigeminal nerve and the arteries by making a tiny incision in your head and moving any arteries that are in contact with the nerve.

    Your surgeon might remove a vein if it is squeezing the nerve. If arteries aren’t pushing on the trigeminal nerve, doctors may also do a nerveectomy during this treatment.

    Microvascular decompression is a good long-term pain management technique; nonetheless, 3 out of 10 patients will experience a 10-year pain recurrence. A stroke or other issues, as well as diminished hearing, facial paralysis, and face numbness, are possible side effects of microvascular decompression. After this operation, the majority of patients experience no facial numbness.

 

  • Gamma knife stereotactic radiosurgery of the brain. During this process, a surgeon targets the trigeminal nerve root with a targeted radiation dose. In order to cause damage to the trigeminal nerve and lessen or eliminate pain, this technique uses radiation. Pain subsides gradually over a period of up to one month.

    For most patients, brain stereotactic radiosurgery is helpful in relieving pain. Like any surgery, there is a chance of recurrence, usually within three to five years. Should the pain return, either repeat the operation or try a different one. A common adverse effect that might happen months or years after the treatment is facial numbness.
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